TargetMol

PD-1/PD-L1-IN 6

Product Code:
 
TAR-T61968
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T61968-5mg5mg£850.00
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Quantity:
TAR-T61968-50mg50mg£1,661.00
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Quantity:
TAR-T61968-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
PD-1/PD-L1-IN 6 (compound A13) is a potent inhibitor of PD-1/PD-L1 interaction (IC 50 = 132.8 nM). PD-1/PD-L1-IN 6 shows outstanding immunoregulatory activity. In a Hep3B/OS-8/hPD-L1 and CD3 T cell co-culture model, PD-1/PD-L1-IN 6 significantly elevates interferon-γ secretion without significant toxic effect. In a T cell-tumor co-culture model, PD-1/PD-L1-IN 6 restores the immune response.
CAS:
2393983-76-9
Molecular Weight:
402.494
Purity:
0.98
SMILES:
COc1cc(ccc1CNCCO)C(=O)N1CCc2c1cccc2-c1ccccc1