TargetMol

BS-181 dihydrochloride

Product Code:
 
TAR-T62774
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T62774-5mg5mg£850.00
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Quantity:
TAR-T62774-50mg50mg£1,661.00
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Quantity:
TAR-T62774-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BS-181 dihydrochloride is a selective and potent inhibitor of CDK7 with an IC50 value of 21 nM. BS-181 dihydrochloride inhibits CDK2 (IC50: 880 nM), CDK5 (IC50: 3000 nM) and CDK9 (IC50: 4200 nM), but does not block CDK1, 4 and 6. BS-181 dihydrochloride inhibits the growth of a group of cancer cells (IC50: 11.5 uM-37.3 uM) and induces apoptosis.
CAS:
1883548-83-1
Molecular Weight:
453.46
Purity:
0.98
SMILES:
Cl.Cl.CC(C)c1cnn2c(NCc3ccccc3)cc(NCCCCCCN)nc12