TargetMol

KRAS inhibitor-13

Product Code:
 
TAR-T63164
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T63164-5mg5mg£1,167.00
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Quantity:
TAR-T63164-50mg50mg£2,307.00
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Quantity:
TAR-T63164-100mg100mg£2,898.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
KRAS inhibitor-13 (compound 5-6) is a potent inhibitor of KRAS G12C (IC50: 0.883 uM). KRAS inhibitor-13 has a p-ERK inhibitory effect in MIA PaCA-2, A549 cells with IC50 values of 5.9 and >100 uM respectively. KRAS inhibitor-13 has potential to be studied in pancreatic, colorectal and lung cancers.
CAS:
2230873-96-6
Molecular Weight:
479.95
Purity:
0.98
SMILES:
[H][C@]12CN(c3snc4c(F)c(c(Cl)cc34)-c3cc(O)cc4ccccc34)[C@@]1([H])CCN2C(=O)C=C