TargetMol

Difelikefalin HCl

Product Code:
 
TAR-T69537
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T69537-5mg5mg£1,091.00
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TAR-T69537-50mg50mg£2,143.00
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Quantity:
TAR-T69537-100mg100mg£2,801.00
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This product comes from: United States.
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Further Information

Bioactivity:
Difelikefalin is a κ-opioid receptor (KOR) agonist. It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM). Difelikefalin is selective for KOR over the u-opioid receptor (MOR; EC50 = >1 uM in a transactivation assay). It reduces acetic acid-induced writhing, as well as scratching behavior induced by the KOR antagonist GNTI, in mice (ED50s = 0.07 and 0.05 mg/kg, respectively).
CAS:
2711717-77-8
Molecular Weight:
789.237
Purity:
0.98