TargetMol

PX-316

Product Code:
 
TAR-T69589
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T69589-5mg5mg£2,135.00
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Quantity:
TAR-T69589-50mg50mg£4,231.00
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Quantity:
TAR-T69589-100mg100mg£5,934.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
PX-316 is a AKT inhibior. PX-316, when administered intraperitoneally to mice at 150 mg/kg, inhibits Akt activation in HT-29 human tumor xenografts up to 78% at 10 h with recovery to 34% at 48 h. PX-316 has antitumor activity against early human MCF-7 breast cancer and HT-29 colon cancer xenografts in mice. PX-316 formulated in 20% hydroxypropyl-beta-cyclodextrin for intravenous administration is well tolerated in mice and rats with no hemolysis and no hematological toxicity. Thus, PX-316 is the lead compound of a new class of potential agents that inhibit Akt survival signaling.
CAS:
253440-95-8
Molecular Weight:
584.71994
Purity:
0.98