TargetMol

Tofacitinib HCl

Product Code:
 
TAR-T70168
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T70168-5mg5mg£850.00
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Quantity:
TAR-T70168-50mg50mg£1,661.00
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Quantity:
TAR-T70168-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Tofacitinib, also known as tasocitinib, CP-690550, is a Janus kinase (JAK) inhibitor. Tofacitinib modulates the signaling pathway at the point of JAKs, preventing the phosphorylation and activation of STATs. JAK enzymes transmit cytokine signaling through pairing of JAKs (e.g., JAK1/JAK3, JAK1/JAK2, JAK1/TyK2, JAK2/JAK2). Tofacitinib inhibited the in vitro activities of JAK1/JAK2, JAK1/JAK3, and JAK2/JAK2 combinations with IC50 of 406, 56, and 1377 nM, respectively.
CAS:
1803005-18-6
Molecular Weight:
348.835
Purity:
0.98