TargetMol

CM-352

Product Code:
 
TAR-T70470
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T70470-5mg5mg£1,251.00
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TAR-T70470-50mg50mg£2,464.00
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Quantity:
TAR-T70470-100mg100mg£3,283.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
CM-352 is a potent MMP inhibitor, which inhibited fibrinolysis in human whole blood functional assays and was more effective than the current standard of care, tranexamic acid, in the tail-bleeding model using a 30,000 times lower dose. Moreover, CM-352 reduced blood loss during liver hepatectomy. CM352 displayed optimal pharmacokinetic and safety profiles with no evidence of thrombosis or coagulation impairment. This novel mechanism of action, targeting MMP, defines a new class of antihemorrhagic agents without interfering with normal hemostatic function. Furthermore, CM-352 represents a pre-clinical candidate for the acute treatment of bleeding.
CAS:
1542205-83-3
Molecular Weight:
487.57
Purity:
0.98
SMILES:
S(=O)(=O)([C@@]1(C(NO)=O)CC2(CC1)CCNCC2)C3=CC=C(OC4=CC=C(C(NC)=O)C=C4)C=C3