TargetMol

Maprotiline-d3 hydrochloride

Product Code:
 
TAR-T70960
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T70960-5mg5mg£670.00
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TAR-T70960-50mg50mg£1,661.00
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Quantity:
TAR-T70960-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Maprotiline-d3 is intended for use as an internal standard for the quantification of maprotiline by GC- or LC-MS. Maprotiline is a tricyclic antidepressant. It binds to the norepinephrine transporter (NET) and is selective for NET over the serotonin and dopamine transporters. Maprotiline also binds to the serotonin (5-HT) receptor subtype 5-HT2A, as well as histamine H1, muscarinic acetylcholine, α1-adrenergic, and dopamine D2 receptors. In vivo, maprotiline inhibits norepinephrine reuptake in rat brain and peripheral tissues. It reduces isolation-induced aggressive behavior and inhibits electrical foot-shock stimulation-induced belligerence in mice when administered at doses ranging from 3 to 10 mg/kg. Maprotiline also reduces aggressive behavior in rhesus monkeys housed in groups. Formulations containing maprotiline have been used in the treatment of depression and anxiety.
CAS:
1329496-63-0
Molecular Weight:
316.8873
Purity:
0.98
SMILES:
Cl.[2H]C([2H])([2H])NCCCC12CCC(c3ccccc13)c1ccccc21