TargetMol

CIA-1 hcl(452087-38-6 Free base)

Product Code:
 
TAR-T71534
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T71534-5mg5mg£850.00
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TAR-T71534-50mg50mg£1,661.00
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Quantity:
TAR-T71534-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 uM to 7.6 uM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII activity to regulate its target genes.CIA-1 in vivo exhibits tumor growth inhibitory effects in a mouse model of prostate cancer xenografts. inhibitory effect on tumor growth in a xenograft mouse model of prostate cancer in vivo.
CAS:
1049691-47-5
Molecular Weight:
365.88
Pathway:
Neuroscience|Stem Cells|Proteases/Proteasome
Purity:
0.98
SMILES:
Cl.N=1C=NC(NCCC2=CC=C(OC)C(OC)=C2)=C3C=C(SC13)C
Target:
Gamma-secretase

References

Matsumoto T, et al. Characterization of CIA-1, an Ambler class A extended-spectrum ?-lactamase from Chryseobacterium indologenes. Antimicrob Agents Chemother. 2012;56(1):588-590. Renshaw RW, et al. A hypervariable region in VP1 of chicken infectious anemia virus mediates rate of spread and cell tropism in tissue culture. J Virol. 1996;70(12):8872-8878.