TargetMol

Syntelin

Product Code:
 
TAR-T71828
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T71828-5mg5mg£850.00
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Quantity:
TAR-T71828-50mg50mg£1,661.00
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Quantity:
TAR-T71828-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Syntelin is a selectively CENP-E inhibitor. Syntelin inhibited CENP-E motility in a dose-dependent manner with an IC50 value of 160 nM. Among an extensive list of mitotic kinesins examined, syntelin was found to be highly selective for CENP-E. Syntelin binds to different sites from those of GSK923295, a recently identified CENP-E ATPase inhibitor, as syntelin inhibits CENP-E mutants resistant to GSK923295 in a manner indistinguishable from that of wild type motor. Syntelin represents a novel class of CENP-E motor inhibitor.
CAS:
438481-33-5
Molecular Weight:
484.62
Purity:
0.98
SMILES:
Nc1nc(SCc2nnc(SCC(O)=O)n2-c2ccccc2)nc2sc3CCCCc3c12