TargetMol

ZIM

Product Code:
 
TAR-T72024
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T72024-5mg5mg£115.00
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Quantity:
TAR-T72024-1mL1 mL * 10 mM (in DMSO)£135.00
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Quantity:
TAR-T72024-10mg10mg£142.00
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Quantity:
TAR-T72024-25mg25mg£213.00
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Quantity:
TAR-T72024-50mg50mg£308.00
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Quantity:
TAR-T72024-100mg100mg£453.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
ZIM, a norbornene derived from 4-Aminoantipyrine, is a potent inducer of DNA damage, causing genomic and chromosomal damage as well as inducing cell death and activating phagocytosis. ZIM has chemotherapeutic potential for use in cancer research .
CAS:
301298-87-3
Formula:
C20H19N3O3
Molecular Weight:
349.38
Purity:
0.9913
SMILES:
O=C1C(=C(N(N1C=2C=CC=CC2)C)C)N3C(=O)C4C5C=CC(C5)C4C3=O

References

Chung HS, et al. A critical role for the TIFY motif in repression of jasmonate signaling by a stabilized splice variant of the JASMONATE ZIM-domain protein JAZ10 in Arabidopsis. Plant Cell. 2009;21(1):131-145. Shikata M, et al. Characterization of Arabidopsis ZIM, a member of a novel plant-specific GATA factor gene family. J Exp Bot. 2004;55(397):631-639. Oliveira RJ, et al. ZIM, a Norbornene Derived from 4-Aminoantipyrine, Induces DNA Damage and Cell Death but in Association Reduces the Effect of Commercial Chemotherapeutics. Chem Res Toxicol. 2023;36(1):66-82.