TargetMol

A2AR-antagonist-1

Product Code:
 
TAR-T72626
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T72626-5mg5mg£850.00
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Quantity:
TAR-T72626-50mg50mg£1,661.00
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Quantity:
TAR-T72626-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
A2AR-antagonist-1 is an orally active adenosine A2A receptor (A2AR) antagonist ( IC 50 =29 nM). A2AR-antagonist-1 exhibits anti-tumor activity and mouse liver microsomal metabolic stability (t 1/2 =86.1 min). A2AR-antagonist-1 is also a T cells activator, via inhibiting immunosuppressive molecules (LAG-3 and TIM-3) and enhancing effector molecules (GZMB, IFNG, and IL-2) .
Molecular Weight:
451.52
Purity:
0.98
SMILES:
CC1=C(C=CC=C1C2=NC(=NC(=C2)C3=CC(=O)N(C=C3)CC4=CC(=CC=C4)C(C)(C)O)N)C#N