TargetMol

Sofnobrutinib

Product Code:
 
TAR-T72865
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T72865-5mg5mg£1,091.00
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TAR-T72865-50mg50mg£2,143.00
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Quantity:
TAR-T72865-100mg100mg£2,801.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Sofnobrutinib (AS-0871) is an orally active and selective BTK inhibitor, with IC 50 s of 4.2 nM (activated BTK ) and 0.39 nM (unactivated BTK ), respectively. Sofnobrutinib also inhibits hERG with an IC 50 value of 24 uM. Sofnobrutinib has good metabolic stability and bioavailability. Sofnobrutinib results poor passive cutaneous anaphylaxis reaction, as well as exerting anti-inflammatory effects in collagen-induced arthritis model in mice .
CAS:
1646608-10-7
Molecular Weight:
498.51
Purity:
0.98
SMILES:
O=C1C=2C(F)=CC(=CC2C=CN1C3=CC=CC(C=4N=C(N=C(N4)NC=5C=NN(C5)C)N)=C3CO)C6CC6