TargetMol

SMTIN-T140

Product Code:
 
TAR-T73125
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T73125-5mg5mg£930.00
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Quantity:
TAR-T73125-50mg50mg£1,821.00
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Quantity:
TAR-T73125-100mg100mg£2,319.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SMTIN-T140 is a potent TRAP1 (tumor-necrosis-factor-receptor associated protein 1) inhibitor, with an IC 50 of 1.646 uM. SMTIN-T140 shows anticancer activity. SMTIN-T140 leads to mitochondrial dysfunction, increases mitochondrial ROS production and activates AMPK . SMTIN-T140 potently suppressed tumor growth without any noticeable in vivo toxicity in a mouse model xenografted with PC3 prostate cancer cells .
Molecular Weight:
718.02
Purity:
0.98
SMILES:
C1=CC=C(C=C1)[P+](CCCCCCN2C3=C(N=C(N=C3Cl)N)N(C2=O)CC4=C(C=C(C=C4)Br)F)(C5=CC=CC=C5)C6=CC=CC=C6