TargetMol

RO5461111

Product Code:
 
TAR-T73220
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T73220-5mg5mg£630.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T73220-50mg50mg£2,303.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T73220-100mg100mg£3,042.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
RO5461111 a highly specific and orally active antagonist of Cathepsin S with IC 50 s of 0.4 nM (human Cathepsin S ) and 0.5 nM (murine Cathepsin S ), respectively. RO5461111 can effectively inhibit the activation of antigen-specific T cells and B cells. RO5461111 can improve pulmonary inflammation and lupus nephritis .
CAS:
1252637-46-9
Molecular Weight:
614.56
Purity:
0.98
SMILES:
C(=O)(C1(C(F)(F)F)CC1)N2[C@H](C(NC3(C#N)CC3)=O)C[C@@H](S(=O)(=O)C4=C(C(F)(F)F)C=C(C=C4)C=5C=C(C)N=CC5)C2