TargetMol

JMX0293

Product Code:
 
TAR-T73419
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T73419-5mg5mg£850.00
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Quantity:
TAR-T73419-50mg50mg£1,661.00
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Quantity:
TAR-T73419-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
JMX0293 is an O-alkylamino-tethered salicylamide derivative compound. JMX0293 maintains good potency against MDA-MB-231 cell line ( IC 50 = 3.38 uM) while exhibiting very low toxicity against human non-tumorigenic breast epithelial cell line MCF-10A ( IC 50 > 60 uM). JMX0293 inhibits STAT3 phosphorylation and contribute to apoptosis in TNBC MDA-MB-231 cells. JMX0293 significantly suppresses MDA-MB-231 xenograft tumor growth in vivo without significant toxicity .
Molecular Weight:
569.43
Purity:
0.98
SMILES:
CC(OC(NCCOC1=C(C=C(C=C1)Cl)C(N[C@@H](C(C)C)C(NC2=C(C=C(C=C2)[N+]([O-])=O)Cl)=O)=O)=O)(C)C