TargetMol

NP10679

Product Code:
 
TAR-T73447
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T73447-5mg5mg£850.00
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Quantity:
TAR-T73447-50mg50mg£1,661.00
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Quantity:
TAR-T73447-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
NP10679 is a selective, pH dependent GluN2B subunit -specific N-methyl-D-aspartate ( NMDA ) receptor inhibitor with high oral bioavailability and good brain penetration. NP10679 inhibits GluN2B with IC 50 s of 23 and 142 nM at pH 6.9 and 7.6, respectively. NP10679 is a histamine H1 antagonist and a hERG channel inhibitor with IC 50 s of 73 and 620 nM, respectively. NP10679 is a reversible inhibitor of human liver CYP enzymes .
Molecular Weight:
449.47
Purity:
0.98
SMILES:
C1CC(=O)NC2=C1C=C(C=C2)OC[C@@H](CN3CCN(CC3)C4=CC=C(C=C4)C(F)(F)F)O