TargetMol

HI5

Product Code:
 
TAR-T73581
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T73581-5mg5mg£850.00
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Quantity:
TAR-T73581-50mg50mg£1,661.00
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Quantity:
TAR-T73581-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
HI5 is a potent tublin and IDO inhibitor, with an IC 50 value of 70 nM in HeLa cells. HI5 inhibit IDO expression and decrease kynurenine production, leading to stimulating T cells activation and proliferation. HI5 can inhibit tubulin polymerization and cell migration, cause G2/M phase arrest, and induce apoptosis via the mitochondrial dependent apoptosis pathway and cause reactive oxidative stress generation in HeLa cells. HI5 can be used for researching anticancer .
CAS:
2411548-90-6
Molecular Weight:
745.82
Purity:
0.98
SMILES:
C(C(C(OCCC1=CN(CC2=CC(C(OC3=C(OC)C=CC(/C=C\C4=CC(OC)=C(OC)C(OC)=C4)=C3)=O)=CC=C2)N=N1)=O)N)C=5C=6C(N(C)C5)=CC=CC6