TargetMol

β-Glucuronide-dPBD-PEG5-NH2

Product Code:
 
TAR-T74437
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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TAR-T74437-50mg50mgEnquire
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TAR-T74437-5mg5mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
β-Glucuronide-dPBD-PEG5-NH2 is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD. β-glucuronide-linkage as a cleavable linker. β-Glucuronide-dPBD-PEG5-NH2, as a proagent of cIRCR201-dPBD, reduces side effects. β-Glucuronide-dPBD-PEG5-NH2 can induce apoptosis and arrest cell cycle. β-Glucuronide-dPBD-PEG5-NH2 has antitumor activity [1] .
CAS:
2246363-68-6
Molecular Weight:
1696.66
Purity:
0.98