TargetMol

SIAIS164018

Product Code:
 
TAR-T74570
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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This product comes from: United States.
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Further Information

Bioactivity:
SIAIS164018 is a PROTAC -based ALK and EGFR degrader, which is designed from Brigatinib , with IC 50 value of 2.5 nM and 6.6 nM for ALK and ALK G1202R, respectively. SIAIS164018 strongly inhibits cancer cells migration and invasion, causes G1 cell cycle arrest and induces apoptosis . SIAIS164018 exhibits better property than Brigatinib [1] .
CAS:
2353492-68-7
Molecular Weight:
883.33
Purity:
0.98