TargetMol

HDAC-IN-53

Product Code:
 
TAR-T74783
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T74783-50mg50mgEnquire
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TAR-T74783-5mg5mgEnquire
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
HDAC-IN-53 is an orally active, and selective HDAC1-3 inhibitor with IC 50 values of 47 nM, 125 nM, and 450 nM, respectively. HDAC-IN-53 does not inhibit class II HDACs (HDAC4, 5, 6, 7, 9; IC 50 >10 uM). HDAC-IN-53 induces caspase-dependent apoptosis . HDAC-IN-53 significantly inhibits the growth of human tumor xenografts in nude mice and murine tumor growth in immune-competent mice bearing MC38 colon cancer [1] .
Molecular Weight:
461.9
Purity:
0.98