TargetMol

JAK3/BTK-IN-1

Product Code:
 
TAR-T9814
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

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CodeSizePrice
TAR-T9814-5mg5mg£430.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T9814-10mg10mg£613.00
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Quantity:
TAR-T9814-25mg25mg£997.00
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Quantity:
TAR-T9814-50mg50mg£1,458.00
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Quantity:
TAR-T9814-100mg100mg£2,155.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important targets in autoimmune diseases. JAK3/ BTk-in-1 simultaneously inhibited the BTK/JAK3 signaling pathway, showing a synergistic effect. JAK3/ BTK-in-1 is a potential compound for the treatment of immune-related diseases, such as autoimmune diseases, certain types of cancer (including lymphoma and leukemia), and other diseases that may be characterized by an unbalanced immune response.
CAS:
2674036-91-8
Molecular Weight:
456.54
Pathway:
Stem Cells|Chromatin/Epigenetic|JAK/STAT signaling|Angiogenesis|Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
N(C1=C2C(=CNC2=NC(NC3=CN(CC)N=C3)=N1)C4=CC=CC=C4)[C@H]5CN(C(C=C)=O)CCC5
Target:
BTK|JAK

References

Guobao Zhang, et al. Pyrimidopyrroles. Patent WO2021147952A1.