TargetMol

Neoechinulin A

Product Code:
 
TAR-TN4635
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-TN4635-5mg5mg£568.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN4635-1mL1 mL * 10 mM (in DMSO)£577.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Bioactivity:
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the phosphorylation of mitogen-activated protein kinase (MAPK) molecule p38, apoptosis signal-regulating kinase 1 (ASK-1) and nuclear translocation of nuclear factor-κB (NF-κB) p65 and p50 subunits, it has a potential to be developed as a modulator of neuroinflammatory process in Alzheimer's disease. Neoechinulin A may ameliorate rotenone toxicity by activating a cytoprotective machinery that requires ATP and antioxidant/anti-nitration activities.
CAS:
51551-29-2
Formula:
C19H21N3O2
Molecular Weight:
323.39
Pathway:
Apoptosis|GPCR/G Protein|NF-κb|MAPK|Immunology/Inflammation|Neuroscience
Purity:
0.98
SMILES:
C[C@@H]1NC(=O)\C(NC1=O)=C\c1c([nH]c2ccccc12)C(C)(C)C=C
Target:
COX|IκB/IKK|Beta Amyloid|NOS|NADPH-oxidase|ASK|NF-κB|p38 MAPK|TNF|Prostaglandin Receptor