TargetMol

Manassantin A

Product Code:
 
TAR-TN4489
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TN4489-10mg10mg£1,099.00
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Quantity:
TAR-TN4489-1mL1 mL * 10 mM (in DMSO)£1,115.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibition of iNOS production and NF-κB activation, and improvements in the antioxidant and anti-inflammatory status.Manassantin A represents a potential therapeutic approach for the treatment of airway allergic-inflammatory diseases. Manassantin A inhibits cAMP-induced melanin production by down-regulating the gene expressions of MITF and tyrosinase in melanocytes.
CAS:
88497-87-4
Molecular Weight:
732.867
Pathway:
Chromatin/Epigenetic|MAPK|GPCR/G Protein|NF-κb|Stem Cells|Immunology/Inflammation|Apoptosis|Angiogenesis|JAK/STAT signaling|Neuroscience
Purity:
0.98
SMILES:
[H][C@@]1(O[C@@]([H])([C@H](C)[C@H]1C)c1ccc(O[C@H](C)[C@H](O)c2ccc(OC)c(OC)c2)c(OC)c1)c1ccc(O[C@H](C)[C@H](O)c2ccc(OC)c(OC)c2)c(OC)c1
Target:
cAMP|COX|ERK|MAPK|NF-κB|HIF|TNF|Prostaglandin Receptor|JNK|STAT