TargetMol

4-Desmethyl Istradefylline

Product Code:
 
TAR-T10139
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
4-Desmethyl Istradefylline is a Istradefylline metabolite. Istradefylline is a very potent, selective, and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.
CAS:
160434-48-0
Formula:
C19H22N4O4
Molecular Weight:
370.4
Purity:
0.98
SMILES:
CN1C2=C(N(CC)C(=O)N(CC)C2=O)N=C1/C=C/C3=CC(OC)=C(O)C=C3

References

Chen JF, et al. Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease. J Neurosci. 2001 May 15;21(10):RC143.