TargetMol

6-Hydroxybenzbromarone

Product Code:
 
TAR-T10182
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
6-Hydroxybenzbromarone is the major metabolite of Benzbromarone. 6-Hydroxybenzbromarone is a protein Eyes Absent 3 (EYA3) inhibitor (IC50: 21.5 uM). It is an angiogenic agent, has strong inhibitory effects on cell migration, tubulogenesis, and angiogenic sprouting.
CAS:
152831-00-0
Formula:
C17H12Br2O4
Molecular Weight:
440.08
Purity:
0.98
SMILES:
O=C(C1=CC(Br)=C(O)C(Br)=C1)C=2C=3C=CC(O)=CC3OC2CC

References

Pandey RN, et al. Structure-activity relationships of benzbromarone metabolites and derivatives as EYA inhibitory anti-angiogenic agents.PLoS One. 2013 Dec 18;8(12):e84582.