TargetMol

7-Desmethyl-3-hydroxyagomelatine

Product Code:
 
TAR-T10192
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
7-Desmethyl-3-hydroxyagomelatine is a metabolite of Agomelatine and has less activity than Agomelatine. Agomelatine is a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.
CAS:
166527-00-0
Formula:
C14H15NO3
Molecular Weight:
245.27
Pathway:
Neuroscience|GPCR/G Protein
Purity:
0.98
SMILES:
O=C(NCCC1=CC(O)=CC2=CC=C(O)C=C21)C
Target:
5-HT Receptor

References

Kennedy SH, et al. Agomelatine and its therapeutic potential in the depressed patient. Neuropsychiatr Dis Treat. 2007 Aug;3(4):423-8. Li M, et al. Development and validation a LC-MS/MS method for the simultaneous determination of agomelatine and its metabolites, 7-desmethyl-agomelatine and 3-hydroxy-agomelatine in human plasma: Application to a bioequivalence study. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 15;1003:60-6.