TargetMol

Gamma-glutamylcysteine TFA

Product Code:
 
TAR-T11357
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Gamma-glutamylcysteine (TFA) also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) and attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes. Gamma-glutamylcysteine (TFA) ((γ-glutamylcysteine (TFA)), an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx).
CAS:
283159-88-6
Formula:
C10H15F3N2O7S
Molecular Weight:
364.29
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
OC(=O)C(F)(F)F.N[C@@H](CCC(=O)N[C@H](CS)C(O)=O)C(O)=O
Target:
IL Receptor

References

Braidy N, et al. The Precursor to Glutathione (GSH), ?-Glutamylcysteine (GGC), Can Ameliorate Oxidative Damage and Neuroinflammation Induced by A?40 Oligomers in Human Astrocytes. Front Aging Neurosci. 2019 Aug 8;11:177.