TargetMol

Nilotinib-d6

Product Code:
 
TAR-T12224
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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This product comes from: United States.
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Further Information

Bioactivity:
Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity.
CAS:
1268356-17-7
Formula:
C28H22F3N7O
Molecular Weight:
535.55
Purity:
0.98
SMILES:
C(F)(F)(F)C=1C=C(C=C(NC(=O)C2=C(C(NC=3N=C(C=CN3)C=4C=CC=NC4)=C(C([2H])([2H])[2H])C(=C2[2H])[2H])[2H])C1)N5C=NC(C)=C5

References

Weisberg E, et al. Beneficial effects of combining nilotinib and imatinib in preclinical models of BCR-ABL+ leukemias. Blood. 2007 Mar 1;109(5):2112-20.