TargetMol

TAP311

Product Code:
 
TAR-T13079
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T13079-100mg100mgEnquire
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Further Information

Bioactivity:
TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM).
CAS:
T13079
Formula:
C34H40F6N6O4
Molecular Weight:
710.71
Pathway:
Metabolism
Purity:
0.98
SMILES:
FC(F)(F)C1=CC(CN([C@@H]2C[C@H](CC)N(C(O[C@@H]3CC[C@@H](C(O)=O)CC3)=O)[C@H](CC)C2)C4=NC=C(C5=CN(C)N=C5)C=N4)=CC(C(F)(F)F)=C1
Target:
CETP

References

Yamada K, et al. Discovery of a Novel Piperidine-Based Inhibitor of Cholesteryl Ester Transfer Protein (CETP) That Retains Activity in Hypertriglyceridemic Plasma. J Med Chem. 2017 Oct 26;60(20):8466-8481.