TargetMol

Topiramate D12

Product Code:
 
TAR-T13185
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T13185-100mg100mgEnquire
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TAR-T13185-500mg500mgEnquire
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Further Information

Bioactivity:
Topiramate D12 is a deuterium labeled Topiramate. Topiramate is an agent of broad-spectrum antiepileptic. Topiramate is an antagonist of GluR5 receptor.
CAS:
1279037-95-4
Formula:
C12H21NO8S
Molecular Weight:
351.44
Purity:
0.98
SMILES:
C(OS(N)(=O)=O)[C@]12[C@]([C@]3([C@@](CO1)(OC(C([2H])([2H])[2H])(C([2H])([2H])[2H])O3)[H])[H])(OC(C([2H])([2H])[2H])(C([2H])([2H])[2H])O2)[H]

References

Kaminski RM, et al. Topiramate selectively protects against seizures induced by ATPA, a GluR5 kainate receptor agonist. Neuropharmacology. 2004 Jun;46(8):1097-104. Lyseng-Williamson KA, et al. Topiramate: a review of its use in the treatment of epilepsy. Drugs. 2007;67(15):2231-56. Nakamura J, et al. Target pharmacology of topiramate, a new antiepileptic drug. Nihon Yakurigaku Zasshi. 2000 Jan;115(1):53-7.