TargetMol

FKBP12 PROTAC RC32

Product Code:
 
TAR-T13694
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T13694-100mg100mgEnquire
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Further Information

Bioactivity:
FKBP12 PROTAC RC32 contains conjugation of Rapamycin and a ligand for an E3 ubiquitin ligase.FKBP12 PROTAC RC32 (RC32) is a potent FKBP12 degrader based on PROTAC technology.
CAS:
2375555-66-9
Formula:
C75H107N7O20
Molecular Weight:
1426.69
Purity:
0.98
SMILES:
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCOCCOCCN4C=C(COCCO[C@H]5[C@H](OC)C[C@H](C[C@@H](C)[C@]6(OC(=O)[C@]7(N(C(=O)C(=O)[C@]8(O)O[C@](C[C@H](OC)\C(\C)=C\C=C\C=C\[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)\C(\C)=C\[C@@H](C)C(=O)C6)(CC[C@H]8C)[H])CCCC7)[H])[H])CC5)N=N4

References

A chemical approach for global protein knockdown from mice to non-human primates. Cell Discov. 2019 Feb 5;5:10.