TargetMol

Bis-propargyl-PEG4

Product Code:
 
TAR-T14657
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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This product comes from: United States.
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Further Information

Bioactivity:
Bis-propargyl-PEG4 is a PEG-based PROTAC linker utilized in PROTAC synthesis and specifically employed in the synthesis of demethylvancomycin dimers[1][2].
CAS:
159428-42-9
Formula:
C14H22O5
Molecular Weight:
270.32
Purity:
0.98
SMILES:
C#CCOCCOCCOCCOCCOCC#C

References

Pearlie BURNETTE, et al. Dimeric immuno-modulatory compounds against cereblon-based mechanisms. WO2020014489A2. Jiang, et al. Design, synthesis and biological activity of novel demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis. Tetrahedron, 2018: 74(27), 3527?3533.