TargetMol

(S,R,S)-AHPC-PEG4-NH2 hydrochloride

Product Code:
 
TAR-T15190
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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Further Information

Bioactivity:
(S,R,S)-AHPC-PEG4-NH2 hydrochloride is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating the VHL ligand based on (S,R,S)-AHPC, and a 4-unit PEG linker, which are specifically designed for use in PROTAC technology.
CAS:
2064292-52-8
Formula:
C32H50ClN5O8S
Molecular Weight:
700.29
Purity:
0.98
SMILES:
C([C@@H](NC(COCCOCCOCCOCCN)=O)[C@@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C=3SC=NC3C)=O)C[C@@H](O)C1.Cl

References

Crew, Andrew P, et al. MDM2-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. US20170008904A1.