TargetMol

Hydroxy-PEG10-Boc

Product Code:
 
TAR-T15514
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T15514-500mg500mgEnquire
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Further Information

Bioactivity:
Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024)[1]. Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel or docetaxel [2].
CAS:
778596-26-2
Formula:
C27H54O13
Molecular Weight:
586.71
Purity:
0.98
SMILES:
O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

References

Miller ML, et al. Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific delivery.J Med Chem. 2004 Sep 23;47(20):4802-5. Huli, et al. A kind of preparation method of hydroxyl polyethylene glycol propionic ester. Patent