TargetMol

m-PEG4-Br

Product Code:
 
TAR-T15872
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab. m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency[1].
CAS:
110429-45-3
Formula:
C9H19BrO4
Molecular Weight:
271.15
Purity:
0.98
SMILES:
BrCCOCCOCCOCCOC

References

Walker JA, et al. Hydrophilic Sequence-Defined Cross-Linkers for Antibody-Drug Conjugates.Bioconjug Chem.?2019 Nov 20;30(11):2982-2988.