TargetMol

Mal-amido-PEG2-NHS ester

Product Code:
 
TAR-T15951
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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This product comes from: United States.
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Further Information

Bioactivity:
Mal-amido-PEG2-NHS ester is a noncleavable linker for antibody-drug conjugates (ADCs) that consists of a maleimide group and an NHS ester. The NHS ester allows for the labeling of protein primary amines (-NH2), amine-modified oligonucleotides, and other amine-containing molecules[1][2].
CAS:
955094-26-5
Formula:
C18H23N3O9
Molecular Weight:
425.39
Purity:
0.98
SMILES:
O=C(ON1C(=O)CCC1=O)CCOCCOCCNC(=O)CCN2C(=O)C=CC2=O

References

Hansen AM, et al. Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. Eur J Med Chem. 2019 Apr 15;168:134-145. Zhang ge, et al. Preparation and application of FAPalpha activated polypeptide magnetic nanosphere compound used for diagnosis of tumors. CN105524141A