TargetMol

NH2-PEG2-C2-Boc

Product Code:
 
TAR-T16311
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T16311-500mg500mgEnquire
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Further Information

Bioactivity:
NH2-PEG2-C2-Boc is a polyethylene glycol (PEG)-based PROTAC linker utilized for synthesizing PROTACs[1]. It serves as a non-cleavable 2-unit PEG linker for antibody-drug conjugates (ADCs) in their synthesis[2].
CAS:
756525-95-8
Formula:
C11H23NO4
Molecular Weight:
233.3
Purity:
0.98
SMILES:
O=C(OC(C)(C)C)CCOCCOCCN

References

Joshua D. Thomas, et al. Pyrrolobenzodiazepine antibody conjugates. WO2019126691A1. Han X, et al. Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer. J Med Chem. 2019 Jan 24;62(2):941-964.