TargetMol

VH032-PEG3-acetylene

Product Code:
 
TAR-T17230
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T17230-100mg100mgEnquire
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TAR-T17230-500mg500mgEnquire
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Further Information

Bioactivity:
VH032-PEG3-acetylene is a synthesized conjugate compound consisting of a VH032-based VHL ligand and a linker, designed for use in PROTAC technology as an E3 ligase ligand-linker conjugate[1].
CAS:
2098799-80-3
Molecular Weight:
614.75
Purity:
0.98
SMILES:
C([C@@H](NC(COCCOCCOCC#C)=O)[C@@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1

References

Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.