TargetMol

7-O-(Amino-PEG4)-paclitaxel

Product Code:
 
TAR-T17343
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
7-O-(Amino-PEG4)-paclitaxel is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
CAS:
T17343
Molecular Weight:
1101.19
Purity:
0.98
SMILES:
O[C@@]1([C@@H](OC(C2=CC=CC=C2)=O)C3[C@@]4(C)[C@@H](OC(CCOCCOCCOCCOCCN)=O)C[C@@H]5[C@@]3(OC(C)=O)CO5)C[C@H](OC([C@H](O)[C@@H](NC(C6=CC=CC=C6)=O)C7=CC=CC=C7)=O)C(C)=C([C@@H](OC(C)=O)C4=O)C1(C)C

References

An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562