TargetMol

Acetylene-linker-Val-Cit-PABC-MMAE

Product Code:
 
TAR-T17351
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Acetylene-linker-Val-Cit-PABC-MMAE (LCB14-0602) consists the ADCs linker (Acetylene-linker-Val-Cit-PABC) and potent tubulin inhibitor (MMAE). Acetylene-linker-Val-Cit-PABC-MMAE (LCB14-0602) is a drug-linker conjugate for ADC.
CAS:
1411977-95-1
Molecular Weight:
1307.62
Purity:
0.98
SMILES:
[C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(NC([C@@H](NC([C@@H](NC(COCCOCCOCC#C)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C3)=O)C)C(C)C)=O)[C@@H](C)C)=O)C)([C@H](CC)C)[H])OC)=O)CCC2)[H]

References

PROTEIN-ACTIVE AGENT CONJUGATES AND METHOD FOR PREPARING THE SAME. WIPO Patent Application WO/2012/153193.