TargetMol

CL2A

Product Code:
 
TAR-T17732
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T17732-100mg100mgEnquire
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TAR-T17732-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
CL2A is a pH-sensitive, cleavable PEG8- and triazole-containing PABC-peptide-mc linker, characterized by its ability to induce a bystander effect. It forms a disulfide bond with an antibody at a cysteine residue. Labetuzumab govitecan utilizes this linker for its drug conjugation[1].
CAS:
1846605-04-6
Molecular Weight:
1106.22
Purity:
0.98
SMILES:
C(C1CCC(C(NCC2=CN(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(COCC(N[C@H](C(NC3=CC=C(COC(O)=O)C=C3)=O)CCCCN)=O)=O)N=N2)=O)CC1)N4C(=O)C=CC4=O

References

Samantha Congreve, et al. Antibody drug conjugates (ADC). Teknisk- naturvetenskaplig fakultet