TargetMol

cIAP1 ligand 2

Product Code:
 
TAR-T17869
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T17869-100mg100mgEnquire
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TAR-T17869-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
cIAP1 ligand 2, a derivative of LCL161, is an IAP ligand that can be connected to the ABL ligand for protein via a linker, resulting in the formation of SNIPER.
CAS:
2357114-70-4
Molecular Weight:
632.77
Purity:
0.98
SMILES:
C([C@@H](NC([C@@H](N(C(OCC1=CC=CC=C1)=O)C)C)=O)[C@H]2CCCCC2)(=O)N3[C@@](CCC3)(C4=NC(C(=O)C5=CC(O)=CC=C5)=CS4)[H]

References

Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.