TargetMol

cIAP1 Ligand-Linker Conjugates 14

Product Code:
 
TAR-T17889
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
cIAP1 Ligand-Linker Conjugates 14 consist of an IAP ligand that targets the E3 ubiquitin ligase and a PROTAC linker. These conjugates, known as cIAP1 Ligand-Linker Conjugates 14, are used in the development of SNIPERs[1].
CAS:
1351169-40-8
Molecular Weight:
719.82
Purity:
0.98
SMILES:
C(OC(N[C@H](CC1=CC=CC=C1)[C@@H](C(N[C@H](C(NCCOCCOCCOCC(O)=O)=O)CC(C)C)=O)O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

References

Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.