TargetMol

Gly-Gly-Gly-PEG4-DBCO

Product Code:
 
TAR-T17987
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Gly-Gly-Gly-PEG4-DBCO is a cleavable tetraethylene glycol (PEG) linker comprising of four units. It is primarily employed in the synthesis of antibody-drug conjugates (ADCs)[1].
CAS:
2353409-80-8
Molecular Weight:
694.77
Purity:
0.98
SMILES:
O=C(NCC(=O)NCC(=O)NCCOCCOCCOCCOCCNC(=O)CCC(=O)N1C=2C=CC=CC2C#CC=3C=CC=CC3C1)CN

References

Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.