TargetMol

Mal-VC-PAB-ABAEP-Azonafide

Product Code:
 
TAR-T18304
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Mal-VC-PAB-ABAEP-Azonafide is a drug-linker conjugate for ADC with with potent antitumor activity by using Azonafide (a cytotoxin), linked via the ADC linker Mal-VC-PAB[1].
CAS:
2259318-48-2
Molecular Weight:
1150.28
Purity:
0.98
SMILES:
O=C1C2=C3C(=CC=4C2=CC=CC4)C(OC)=CC=C3C(=O)N1CCN5CCN(CCNC(=O)C6=CC=C(NC(OCC7=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN8C(=O)C=CC8=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C7)=O)C=C6)CC5

References

LANNUTTI, Brian, et al. ROR1 ANTIBODY IMMUNOCONJUGATES. WO 2018/237335 Al.