TargetMol

Vc-seco-DUBA

Product Code:
 
TAR-T18362
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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This product comes from: United States.
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Further Information

Bioactivity:
Vc-seco-DUBA is a drug-linker conjugate for ADC with potent antitumor activity by using DUBA (DNA alkylating agent), linked via the ADC linker Vc-seco[1].
CAS:
1345681-58-4
Molecular Weight:
1331.81
Purity:
0.98
SMILES:
C(Cl)[C@H]1C2=C(N(C(=O)C=3N=C4N(C3)C=C(NC(=O)C5=CC=C(O)C=C5)C=C4)C1)C=C(OC(N(CCN(C(OCC6=CC=C(NC([C@@H](NC([C@@H](NC(OCCOCCN7C(=O)C=CC7=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C6)=O)C)CCOCCO)=O)C=8C2=C(C)C=CC8

References

Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.