TargetMol

N-(5-Hydroxypentyl)maleimide

Product Code:
 
TAR-T18369
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker, commonly employed in the synthesis of antibody-drug conjugates (ADCs). It serves as a crucial component in the production of Gemcitabine-O-Si(di-iso)-O-Mc, an ADC compound [1].
CAS:
180608-78-0
Formula:
C9H13NO3
Molecular Weight:
183.2
Purity:
0.98
SMILES:
O=C1C=CC(=O)N1CCCCCO

References

Finniss, M. C., et al. A versatile acid-labile linker for antibody?drug conjugates. Med. Chem. Commun., 2014, 5(9), 1355-1358.