TargetMol

Pip-alkyne-Ph-COOCH3

Product Code:
 
TAR-T18545
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T18545-100mg100mgEnquire
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TAR-T18545-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Pip-alkyne-Ph-COOCH3 is an alkyl-chain based PROTAC linker utilized for the synthesis of PROTAC ARD-266[1].
CAS:
2308496-47-9
Formula:
C15H17NO2
Molecular Weight:
243.3
Purity:
0.98
SMILES:
O=C(OC)C1=CC=C(C#CC2CCNCC2)C=C1

References

Han X, et al. Discovery of Highly Potent and Efficient PROTAC Degraders of Androgen Receptor (AR) by Employing Weak Binding Affinity VHL E3 Ligase Ligands. J Med Chem. 2019 Dec 26;62(24):11218-11231.