TargetMol

Imatinib carbaldehyde

Product Code:
 
TAR-T18592
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Imatinib carbaldehyde (also known as CGP-57148B carbaldehyde) is a compound derived from Imatinib, an inhibitor of the ABL protein. Imatinib carbaldehyde binds to the IAP ligand with the assistance of a linker, resulting in the formation of SNIPER[1].
CAS:
1436868-85-7
Molecular Weight:
507.59
Purity:
0.98
SMILES:
O=CN1CCN(CC2=CC=C(C=C2)C(=O)NC3=CC=C(C(=C3)NC=4N=CC=C(N4)C5=CN=CC=C5)C)CC1

References

Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.